Page 41 - 21st Century Perspective - Glaucoma Supplement

Figure 23.​ An allergic reaction to the original 0.2% concentration of brimonidine. This can occur with the 0.15% and 0.1%
concentrations as well, but is less common.

Carbonic anhydrase inhibitors

The next to last category of commonly used glaucoma medicines is represented by two clinically
equal topical carbonic anhydrase inhibitors: dorzolamide 2% ophthalmic solution (original brand
name, Trusopt [Merck]), and brinzolamide 1% ophthalmic suspension (original brand name Azopt
[Alcon]) ​(Figure 24)​. Note that brinzolamide is the only suspension glaucoma medicine (except for
Simbrinza [Alcon], which contains brinzolamide, which also makes it a suspension formulation).

Figure 24.​ Trusopt and Azopt carbonic anhydrase inhibitors.

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