Page 30 - 21st Century Perspective - Glaucoma Supplement

Figure 17.​ This patient developed periorbitopathy after a few years on a prostaglandin.

Some years later, Travatan Z (travoprost, Alcon), which is BAK-free, and Lumigan (bimatoprost,
Allergan) entered the market, followed by tafluprost (Zioptan, Akorn), which is the only
preservative-free prostaglandin, a few years later ​(Figure 18)​. Like latanoprost, tafluprost is stored
under refrigeration until dispensed to the patient.

Figure 18.​ Latanprost, travoprost (Travatan Z), bimatoprost (Lumigan) and tafluprost (Zioptan) ophthalmic solutions.

The prostaglandin market had a quiescent period for several years until November 2017, when
Vyzulta (latanoprostene bunod 0.024%, Bausch + Lomb) broke the silence ​(Figure 19)​.

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